The Proteasome — Ubiquitin Protein Degradation Pathway

This volume gives a complete overview of the structure and function of the proteasome, its regulators and inhibitors, and its cellular importance, in conjunction with the ubiquitin system, for the degradation of regulatory proteins and the generation of immunogenic peptides. The topics range from the molecular evolution of the proteasome and its associated activators, the proteasome in the immune response, to proteasome inhibitors.